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Über eine Substitutionsreaktion bei 3‐Benzoyloxy‐cholesten‐(1) durch Aluminiumoxyd: Untersuchung mit Hilfe von isotopem Sauerstoff
Author(s) -
Dahn H.,
Menassé R.,
Tamm Ch.
Publication year - 1959
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19590420647
Subject(s) - chemistry , medicinal chemistry , alcohol , solvent , labelling , organic chemistry , biochemistry
By labelling with 18 O it was shown that the reaction of the ester 3β‐benzoyloxycholestene‐(1) (I*) in an unpolar solvent on alumina to give the alcohol 3α‐hydroxycholestene‐(1) (II) occurs with alkyl‐O‐fission. The alcohol 3β‐hydroxy‐cholestene‐( 1) (IV*) corresponding to I* remained practically unchanged under these conditions.