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Synthesen in der Carotinoid‐Reihe. 15. Mitteilung Synthesen in der β‐Carotinal‐ und β‐Carotinal‐Reihe
Author(s) -
Rüegg R.,
Montavon M.,
Ryser G.,
Saucy G.,
Schwieter U.,
Isler O.
Publication year - 1959
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19590420328
Subject(s) - chemistry , polyene , ether , stereochemistry , medicinal chemistry , organic chemistry
To study the oxidative degradation of p‐carotene to vitamin A in the animal body, a number of possible intermediates have been prepared. Starting with 15,15′‐dehydro‐β‐apo‐12′‐carotenal(C 25 ) vinylogous series of polyene aldehydes and acetates with 25 to 40 carbon atoms have been synthesized by successive enol ether condensations. The synthetic β‐apo‐8′‐carotenal(C 30 ) and β‐apo‐8′‐carotenal(C 30 ) were identical with the permanganate oxidation product of β‐carotene and its corresponding alcohol isolated by K ARRER .