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Hydroxy‐morphinane. 12. Mitteilung . Die Konfiguration der Morphinane
Author(s) -
Corrodi H.,
Hellerbach J.,
Züst A.,
Hardegger E.,
Schnider O.
Publication year - 1959
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19590420119
Subject(s) - chemistry , steric effects , stereochemistry , acetic acid , organic chemistry
It has been shown that synthetic (–)‐3‐hydroxy‐N‐methyl‐morphinane (I) possesses the same steric configuration at the C‐atoms 9, 13 and 14 as the natural mor‐phine alkaloids, since it can be degraded to the known (–)‐ cis ‐ [2‐methyl‐carboxy‐cyclohexyl‐(l)]‐acetic‐acid.