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Heilmittelchemische Studien in der heterocyclischen Reihe. 22. Mitteilung. Pyrazolo‐pyrimidine II. Pyrazolo[3,4‐d]pyrimidine mit Koffein‐ähnlicher Struktur und Wirkung
Author(s) -
Schmidt P.,
Eichenberger K.,
Druey J.
Publication year - 1958
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19580410418
Subject(s) - chemistry , pyrimidine , medicinal chemistry , stereochemistry
The preparation of the caffeine isomers 1,5,7‐ and 2,5,7‐trimethyl‐4, 6‐dioxo‐4,5,6,7‐tetrahydro‐pyrazolo[3,4‐d]pyrimidines is described and their structures established. The compounds exhibit diuretic and cardiac activity.