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Zur Kenntnis der Triterpene. 193. Mitteilung. Synthese von (±)‐ trans ‐4,4,7,9‐Tetramethyl‐3β‐hydroxy‐decalon‐(8)
Author(s) -
Kalvoda J.,
Loeffel H.
Publication year - 1957
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19570400731
Subject(s) - chemistry , stereochemistry , triterpene , medicine , pathology , alternative medicine
Racemic trans‐4,4,7,9‐tetramethyl‐3 β‐hydroxy‐decalone‐(8) (Xa) has been synthesized. The corresponding optically active levorotatory compound had been previously obtained by R. Rüegg, J. Dreiding, O. Jeger and L. Ruzicka, as a degradation product of α‐amyrin. The stereoisomer racemic cis‐4,4,7,9‐tetramethyl‐3 α‐hydroxy‐decalone‐(8) (XIVa) and the two hydroxyketones (±)‐trans‐4,4,7‐trimethyl‐3 β‐hydroxy‐decalone‐(8) (XIIIa) and (±)‐cis‐4,4,7‐trimethyl‐3 β‐hydroxy‐decalone‐(8) (IXa) have also been obtained as secondary products of the synthesis.