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Über Derivate des Phenylbutazons. I. In den Benzolkernen hydroxylierte Derivate
Author(s) -
Pfister R.,
Häfliger F.
Publication year - 1957
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19570400218
Subject(s) - chemistry , phenylbutazone , stereochemistry , medicinal chemistry , pharmacology , medicine
The synthesis of four derivatives of phenylbutazone with one or two hydroxy groups in the phenyl nuclei is described, among them p‐hydroxy‐phenylbutazone [1‐(p‐hydroxyphenyl)‐2‐phenyl‐4‐n‐butylpyrazolidine‐3,5‐dione] (II) which is one of the metabolites of phenylbutazone in man.