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Heilmittelchemische Studien in der heterocyclischen Reihe. 17. Mitteilung. 4,7‐Phenanthrolinchinon‐Derivate mit amoebicider Wirkung
Author(s) -
Schmidt P.,
Druey J.
Publication year - 1957
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19570400212
Subject(s) - chemistry , quinone , medicinal chemistry , stereochemistry
The amebicidal activity of the phenanthroline quinones published earlier 2 ) and of their derivates described in this paper is discussed. The highest activity was found with 4,7‐phenanthrolino‐5, 6‐ quinone 1 and its monosemicarbazone 3 , which are also active in man. Further derivatives of 1 are described.