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Die konkurrierende 1,2‐ und 1,3‐Acylwanderung. Zur Kenntnis des 2‐Oxy‐3,4‐diamino‐pentans. II. Teil 1 )
Author(s) -
Grob C. A.,
Wagner C.
Publication year - 1955
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19550380706
Subject(s) - chemistry , pentane , medicinal chemistry , stereochemistry , organic chemistry
Abstract Reversible 1,2 and 1,3 acyl migrations with retention of configuration are shown to occur in 2‐hydroxy‐3,4‐diamino‐pentane. In 2‐hydroxy‐3,4‐bis(acetylamino)‐pentane, where 1,2 and 1,3 migration of like acyl groupe compete, the former reaction was the only one observed. In 2‐hydroxy‐3‐benzoylamino‐4‐acetylamino‐pentane, where 1,2 benzoyl migration competes with 1,3 acetyl migration, the latter predominated.