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Zur Konstitution des Marinobufagins, II. Mitteilung. Über Krötengifte, 9. Mitteilung
Author(s) -
Pataki Stephan,
Meyer Kuno
Publication year - 1955
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19550380640
Subject(s) - chemistry , stereochemistry , oxygen atom , group (periodic table) , ring (chemistry) , crystallography , molecule , organic chemistry
Marinobufagin, which has the formula C 24 H 32 O 5 , is a 3,5‐dihydroxysteroid on the basis of chemical evidence. β‐Orientation of the C‐5 HO‐group can be deduced from molecular rotation differences between Marinobufagin and some of its derivatives. The spatial arrangement of the HO‐group at C‐3 is most probably the same 1 . Marinobufagin contains no tertiary hydroxyl at C‐14 and the fifth oxygen‐atom of this genin must be located in an oxide‐ring of unknown size, about which no precise statements can be made.