Premium
Über Steroide. 129. Mitteilung. Bildung von 18‐ und 19‐Oxy‐cortexon durch Einwirkung von Nebennieren‐Homogenaten auf Cortexon
Author(s) -
Kahnt F. W.,
Neher R.,
Wettstein A.
Publication year - 1955
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19550380519
Subject(s) - chemistry , incubation , medicinal chemistry , biochemistry
By aerobic incubation of Cortexone with homogenates of beef adrenals the new 18‐hydroxy‐cortexone as well as the already known 19‐hydroxy‐compound are obtained. The implications of the presence of an 18‐hydroxylase for the postulated course of biosynthesis of aldosterone in vitro are discussed.