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Odeur et constitution XI. Etude de la transestérification‐déshydratation de la lactone de l'acide tétraméthyl‐1,1,6,10‐hydroxy‐6‐décalyl‐5‐acétique
Author(s) -
Stoll M.,
Hinder M.
Publication year - 1954
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19540370632
Subject(s) - chemistry , dehydration , sulfuric acid , saponification , acetic acid , transesterification , medicinal chemistry , lactone , organic chemistry , methanol , biochemistry
The transesterification‐dehydration of lactone I (of 1, 1, 6, 10‐tetramethyl‐6‐hydroxy‐decalyl‐5‐acetic acid) yields besides small quantities of isolactone II the ester of the corresponding non saturated acid III. Prolonged heating in the presence of more concentrated sulfuric acid isomerizes this acid into acid IV. If the concentration of the latter reaches 45%, saponification of the reaction products yields no more the acids III m. p. 118° or IV m. p. 102° but an eutectic acid m. p. 84°. The corresponding infrared spectra are discussed.