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Untersuchungen in der Chinuclidin‐Reihe. 1. Mitteilung. Synthese und C‐Alkylierung des 1‐Methyl‐4‐cyano‐piperidins
Author(s) -
Grob C. A.,
Renk E.
Publication year - 1954
Publication title -
helvetica chimica acta
Language(s) - German
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19540370610
Subject(s) - chemistry , piperidine , alkylation , medicinal chemistry , stereochemistry , organic chemistry , catalysis
1‐Methyl‐4‐cyano‐piperidine (XIII), an intermediate in the synthesis of 4‐substituted quinuclidines, has been prepared and its alkylation at the 4‐position studied.