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Heilmittelchemische Studien in der heterocyclischen Reihe. 7. Mitteilung. Pyridazine IV. Derivate des cyclischen Chlormaleinsäure‐phenylhydrazids
Author(s) -
Meier Kd.,
Ringier B. H.,
Druey J.
Publication year - 1954
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19540370215
Subject(s) - chemistry , phenylhydrazine , pyridazine , medicinal chemistry
The reaction between chloromaleic acid anhydride and phenylhydrazine is studied. The constitution of the two isomeric 1‐phenyl‐3‐hydroxy‐chloro‐pyridazones‐(6) is established. Starting with 1‐phenyl‐3‐hydroxy‐4‐chloro‐pyridazone‐(6) some derivatives are prepared. Some of them show good analgesic activity.