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Heilmittelchemische Studien in der heterocyclischen Reihe. 6. Mitteilung. Pyridazine III. Derivate des cyclischen Maleinsäure‐ und Citraconsäure‐phenylhydrazids
Author(s) -
Druey J.,
Hüni A.,
Meier Kd.,
Ringier B. H.,
Staehelin A.
Publication year - 1954
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19540370214
Subject(s) - chemistry , phenylhydrazine , pyridazine , maleic anhydride , medicinal chemistry , organic chemistry , copolymer , polymer
Abstract The reaction of phenylhydrazine with maleic acid anhydride and with citraconic acid anhydride was studied. The cyclic phenylhydrazides (1‐phenyl‐3‐hydroxy‐6‐pyridazones) obtained in this way served as starting materials for the preparation of substituted 1‐phenyl‐6‐pyridazones. Some of them show analgesic and antipyretic activity.