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Coenzym A: Modellreaktionen zur enzymatischen Aktivierung von Acylderivaten des Coenzyms A
Author(s) -
Schwyzer R.,
Hürlimann Ch.
Publication year - 1954
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19540370119
Subject(s) - chemistry , hippuric acid , acylation , stereochemistry , metal ions in aqueous solution , reactivity (psychology) , enzyme , coenzyme a , ion , sulfur , biochemistry , organic chemistry , catalysis , reductase , alternative medicine , pathology , medicine , urine
The reactivity of esters of thiolcarboxylic acids with amino compounds is strongly and specifically enhanced by metal ions possessing affinity for the sulfur atom. Model reactions of the enzymatic acylation of aromatic amines and of the biological synthesis of hippuric acid are described, using benzoyl pantetheine as a model compound for acyl derivatives of coenzyme A, and metal ions as models for the corresponding acetylases.