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Heilmittelchemische Studien in der heterocyclischen Reihe. 5. Mitteilung. Pyridazine II. Eine neue Pyridazinsynthese
Author(s) -
Schmidt P.,
Druey J.
Publication year - 1954
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19540370116
Subject(s) - chemistry , hydrazine (antidepressant) , glyoxal , methylene , pyridazine , medicinal chemistry , carbonic acid , stereochemistry , organic chemistry , chromatography
A new synthesis of 6‐pyridazones starting from three single components is described. The starting materials are (1) and α‐diketone, α‐ketoaldehyde or glyoxal, (2) a carbonic acid having an active methylene group in α‐position, and (3) hydrazine or a monosubstituted hydrazine.