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Über die Herkunft des Kohlenstoff‐Atoms 7 in Cholesterin. Ein Beitrag zur Kenntnis der Biosynthese der Steroide
Author(s) -
Bloch K.
Publication year - 1953
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19530360648
Subject(s) - chemistry , squalene , medicinal chemistry , organic chemistry
Carbon atom 7 in biosynthetic cholesterol is shown to be derived from a methyl carbon of acetic acid. This result is discussed in relation to current hypotheses regarding the biological conversion of squalene to cholesterol.