Premium
Coenzym A. Modellversuche zur biologischen Acylierungsreaktion. Über die Reaktionsfähigkeit von Thiolcarbonsäuren und ihren Estern
Author(s) -
Schwyzer R.
Publication year - 1953
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19530360211
Subject(s) - chemistry , acylation , aqueous solution , cofactor , stereochemistry , medicinal chemistry , organic chemistry , catalysis , enzyme
The reaction between amines and thiolcarboxylic acids and their esters in dilute aqueous solution serves as a model for the biological acylation with coenzyme A. Constitutional influences and the influence of pH on the yields of acid amides are discussed in terms of a hypothesis concerning the mechanism of the reaction.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom