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Time‐varying synchronous cell ensembles during consummatory periods correlate with variable numbers of place cell spikes
Author(s) -
Yagi Saichiro,
Igata Hideyoshi,
Shikano Yu,
Aoki Yuki,
Sasaki Takuya,
Ikegaya Yuji
Publication year - 2018
Publication title -
hippocampus
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.767
H-Index - 155
eISSN - 1098-1063
pISSN - 1050-9631
DOI - 10.1002/hipo.22846
Subject(s) - neuroscience , hippocampal formation , place cell , neurophysiology , spike (software development) , hippocampus , premovement neuronal activity , local field potential , spike train , psychology , biology , computer science , software engineering
Spike rates of a hippocampal place cell are not constant and vary even when an animal visits an identical place field with nearly identical behavior. As one potential neurophysiological source underlying place cell spiking variability, we focused on the temporally fluctuating activity states of neuronal ensembles. Spike patterns of hippocampal neurons were recorded from rats performing a linear track task. Within a single consummatory period, similar sets of neurons were more frequently recruited in synchronous firing events, whereas different synchronized firing patterns of neuronal populations tended to be identified in different consummatory periods. A linear regression analysis indicated that the time‐varying activation patterns of neuronal populations during consummatory periods are correlated with the spike rates of a place cell within its place field during running. These findings suggest that place cell in‐field spiking is not only triggered by static inputs that represent external environments but also strongly depends on the time‐varying internal states of neuronal populations.