Towards a functional organization of the medial temporal lobe memory system: Role of the parahippocampal and medial entorhinal cortical areas | Zendy

Eichenbaum Howard | Zendy; Lipton Paul A. | Zendy

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Towards a functional organization of the medial temporal lobe memory system: Role of the parahippocampal and medial entorhinal cortical areas

Author(s) -

Eichenbaum Howard,

Lipton Paul A.

Publication year - 2008

Publication title -

hippocampus

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.767

H-Index - 155

eISSN - 1098-1063

pISSN - 1050-9631

DOI - 10.1002/hipo.20500

Subject(s) - entorhinal cortex , neuroscience , temporal lobe , hippocampus , episodic memory , context (archaeology) , spatial memory , psychology , parahippocampal gyrus , perirhinal cortex , recognition memory , working memory , cognition , biology , epilepsy , paleontology

Whereas substantial recent evidence has suggested to some that the medial entorhinal cortexá (MEC) plays a specialized role in spatial navigation, here we present evidence consistent with a broader role of the MEC in memory. A consideration of evidence on the anatomy and functional roles of medial temporal cortical areas and the hippocampus, and evidence from recordings from MEC neurons in rats performing a spatial memory task, suggest that the MEC may process information about both spatial and temporal context in support of episodic memory. © 2008 Wiley‐Liss, Inc.

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