Reply

We read with interest the letter by P Dey regarding our article which addresses the role of microbiome in driving intestinal inflammation, barrier disruption and bacterial translocation in CCl 4 -cirrhosis (1). P Dey claims that dysbiosis and inflammation in this model can be attributed, rather than to cirrhosis, to the effects of CCl 4 on the gut microbiome, and that the resultant dysbiosis becomes the major driver of CCl 4 -liver damage. This article is protected by copyright. All rights reserved.