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A molecular link between inflammation and fibrogenesis: The bacterial microflora influences hepatic fibrosis via toll‐like receptor 4–dependent modification of transforming growth factor‐β signaling in hepatic stellate cells
Author(s) -
Luedde Tom,
Trautwein Christian
Publication year - 2008
Publication title -
hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.488
H-Index - 361
eISSN - 1527-3350
pISSN - 0270-9139
DOI - 10.1002/hep.22232
Subject(s) - hepatic stellate cell , tlr4 , toll like receptor , hepatic fibrosis , proinflammatory cytokine , chemokine , downregulation and upregulation , microbiology and biotechnology , kupffer cell , inflammation , signal transduction , transforming growth factor , tlr2 , lipopolysaccharide , fibrosis , receptor , biology , cancer research , immunology , medicine , endocrinology , innate immune system , biochemistry , gene