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Hepatitis C: IIb (IV) or not IIb (IV) that is the question
Author(s) -
Sallie Richard
Publication year - 1995
Publication title -
hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.488
H-Index - 361
eISSN - 1527-3350
pISSN - 0270-9139
DOI - 10.1002/hep.1840220245
Subject(s) - hepatocellular carcinoma , medicine , hepatitis c virus , cirrhosis , viremia , liver disease , hepatitis c , genotype , gastroenterology , immunology , antibody , interferon , virus , biology , biochemistry , gene
Objective : To analyze the distribution of hepatitis C virus (HCV) genotypes among patients positive for antibody to HCV (anti‐HCV) according to age, severity of liver disease, and duration of infection; to investigate the influence of HCV genotypes on response to interferon‐α therapy; and to study HCV viremia levels in relation to genotypes and severity of liver disease. Design : Cross‐sectional study. Setting : 3 university hospitals and 2 research units. Patients : 3 groups of French and Italian patients with chronic HCV infection and detectable serum HCV RNA: Group 1 included 35 patients with hepatocellular carcinoma; group 2, 71 patients with cirrhosis who did not have hepatocellular carcinoma; and group