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Treatment of patients with cirrhosis and refractory ascites using LeVeen shunt with titanium tip: Comparison with therapeutic paracentesis
Author(s) -
Ginès Angels,
Planas Ramon,
Angeli Paolo,
Guarner Carlos,
Salerno Francesco,
Ginès Pere,
Saló Joan,
Rodriguez Nivardo,
Domènech Eugeni,
Soriano Germán,
Anibarro Luis,
Gassull Miguel Angel,
Gatta Angelo,
Arroyo Vicente,
Rodés Juan
Publication year - 1995
Publication title -
hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.488
H-Index - 361
eISSN - 1527-3350
pISSN - 0270-9139
DOI - 10.1002/hep.1840220120
Subject(s) - medicine , paracentesis , ascites , shunt (medical) , cirrhosis , surgery , gastroenterology
It has recently been suggested that insertion of a titanium tip at the venous end of the LeVeen shunt drastically reduces the rate of shunt obstruction. To assess whether the LeVeen shunt with titanium tip improves the results obtained with therapeutic paracentesis, 81 patients with cirrhosis and refractory ascites were randomly assigned to therapy with paracentesis plus intravenous albumin (42 patients) or LeVeen shunt with titanium tip (39 patients). If patients were readmitted for ascites during follow‐up, those in the first group were treated with paracentesis, and those in the LeVeen shunt group by the insertion of a new valve or a new shunt if obstruction was demonstrated. During first hospitalization, both treatments were equally effective in removing ascites. Complications were similar in both groups except for a higher rate of severe bacterial infection in the LeVeen shunt group. The mean duration of hospitalization was shorter in the paracentesis group than in the shunt group. During follow‐up, the total number of readmissions and the number of readmissions for ascites were higher in the paracentesis group than in the shunt group (252 vs. 99, P < .001; and 193 vs. 43, P < .001, respectively). The total time in hospital, however, was similar (38 ± 38 vs. 39 ± 43 days, P = NS). Three patients had obstruction of the shunt during first hospitalization and 14 patients had a total of 22 obstructions during follow‐up. Long‐term survival was similar in both groups. The insertion of a titanium tip at the venous end of the LeVeen shunt does not prevent obstruction. The LeVeen shunt with titanium tip does not provide significant improvement over therapeutic paracentesis in the management of cirrhotic patients with refractory ascites. (H EPATOLOGY 1995; 22:124–131.)