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Pulmonary dysfunction in advanced liver disease
Author(s) -
Kim Sucha
Publication year - 1992
Publication title -
hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.488
H-Index - 361
eISSN - 1527-3350
pISSN - 0270-9139
DOI - 10.1002/hep.1840150231
Subject(s) - medicine , liver transplantation , pulmonary function testing , chronic liver disease , liver disease , etiology , perfusion , liver function tests , shunting , dlco , cardiology , radiology , transplantation , lung , cirrhosis , lung function , diffusing capacity
PURPOSE: Abnormalities in pulmonary function have been reported in association with chronic liver disease of varied etiology. The aim of this study was to better define the frequency and nature of these abnormalities in patients who were being evaluated for liver transplantation. PATIENTS AND METHODS: We performed a battery of pulmonary function tests and chest radiographs in 116 consecutive patients (50 men, 66 women; aged 19 to 70 years, mean 44.6 years) with severe advanced liver disease who were hospitalized specifically for evaluation for possible orthotopic liver transplantation and were able to perform technically satisfactory tests. In 17 patients, quantitative whole‐body technetium‐99m macroaggregated albumin perfusion scanning was also performed for assessment of possible right‐to‐left shunting through intrapulmonary vascular dilatations.