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Ascites in cirrhosis: A medical or surgical problem?
Author(s) -
Shear Leroy
Publication year - 1990
Publication title -
hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.488
H-Index - 361
eISSN - 1527-3350
pISSN - 0270-9139
DOI - 10.1002/hep.1840110226
Subject(s) - peritoneovenous shunt , ascites , medicine , cirrhosis , hepatic encephalopathy , encephalopathy , portal hypertension , surgery , gastroenterology , ascitic fluid , transjugular intrahepatic portosystemic shunt , clearance , urology
Fifty‐seven cirrhotic patients with intractable ascites had a portosystemic shunt. In 35 patients, a peritoneovenous shunt had previously failed. Forty‐six patients were in Pugh's class B and 11 were in class C. There were three operative deaths (5.3%). Fifty‐three (98.2%) of the 54 survivors were cleared of ascites. In one patient, ascites persisted because of postshunt heart failure that resulted in a marked increase of caval pressure. Twenty‐seven patients (50%) had late encephalopathy, which was severe and disabling in 12 (22%). One‐and three‐year survival rates were 72% and 36%, respectively. These results suggest that although portosystemic shunts are remarkably effective in dealing with ascites, the high rate of postoperative encephalopathy is a strong argument against their routine use in the management of intractable ascites in cirrhosis.