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Cocaine‐induced hepatotoxicity
Author(s) -
Porter John M.,
Sussman Marc S.,
Rosen Gerald M.
Publication year - 1988
Publication title -
hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.488
H-Index - 361
eISSN - 1527-3350
pISSN - 0270-9139
DOI - 10.1002/hep.1840080641
Subject(s) - infiltration (hvac) , necrosis , medicine , inflammation , pathology , histopathological examination , physics , thermodynamics
A patient with hepatonecrosis associated with cocaine use is presented. Postmortem examination of the liver showed marked periportal inflammation and necrosis, and mild diffuse fatty infiltration. These pathologic findings are identical to those previously reported in a mouse model of cocaine hepatotoxicity.