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Percutaneous portal‐systemic shunts: Promise and problems
Author(s) -
Zimmon David S.
Publication year - 1988
Publication title -
hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.488
H-Index - 361
eISSN - 1527-3350
pISSN - 0270-9139
DOI - 10.1002/hep.1840080349
Subject(s) - medicine , percutaneous , stent , portal hypertension , inferior vena cava , thrombus , lumen (anatomy) , anastomosis , blood flow , radiology , portography , parenchyma , surgery , pathology , cirrhosis
Original Gianturco expandable stents and their modifications were used to create an experimental intra‐hepatic portacaval anastomosis (EIPCA) in 30 young domestic swine without portal hypertension. The study focused on the design of a suitable stent, the technique of its application, the the evaluation of short‐term patency of the EIPCA. A stent with a 2.5‐cm‐long body and wire skirts on both ends was most suitable for EIPCA creation. Well‐positioned stents shunted most of the portal blood in the inferior vena cava circulation and remained patent for 4–6 weeks. Ingrowth of liver parenchyma and abundant proliferation of the intima and connective tissue inside the stent lumen in these rapidly growing animals gradually decreased EIPCA patency, and thrombus formation with diminished blood flow closed them completely.