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Hepatic granulomata in AIDS
Author(s) -
Stenger Richard J.
Publication year - 1986
Publication title -
hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.488
H-Index - 361
eISSN - 1527-3350
pISSN - 0270-9139
DOI - 10.1002/hep.1840060340
Subject(s) - liver biopsy , biopsy , acid fast , pathology , medicine , staining , granuloma , gastroenterology , tuberculosis , sputum
During a one month period liver biopsy was carried out on eight patients with established acquired immune deficiency syndrome (AIDS) and two suspected of having AIDS to evaluate raised liver enzymes or unexplained fever and weight loss. Each of the 10 patients was found to have hepatic granulomas. Appropriate staining techniques showed acid‐fast bacilli in seven of the liver specimens. One specimen contained numerous Cryptococcal organisms. Two biopsies showed granulomas but no organisms. Liver biopsy was found to be a high yield and rapid diagnostic procedure in patients with AIDS. Our results suggest that hepatic mycobacterial infection may be more common in the syndrome than previously recognized and that liver biopsy specimens should be examined routinely for the presence of acid‐fast bacilli.