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Portal venous‐esophageal luminal pressure gradient in cirrhosis
Author(s) -
Reding Pierre,
Urbain Daniel,
Grivegnee André,
Frere Daniel
Publication year - 1986
Publication title -
hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.488
H-Index - 361
eISSN - 1527-3350
pISSN - 0270-9139
DOI - 10.1002/hep.1840060118
Subject(s) - portal venous pressure , medicine , valsalva maneuver , esophageal varices , expiration , portal hypertension , cirrhosis , pressure gradient , cardiology , venous pressure , hemodynamics , blood pressure , respiratory system , physics , mechanics
The portal venous‐esophageal luminal pressure gradient may be more important than the absolute portal venous pressure in explaining hemorrhages caused by esophageal varices. A continuous recording of portal venous pressure and the esophageal luminal pressure enabled the authors to study the gradient between these pressures in 12 cirrhotic patients with varices of different size and under different circumstances, in particular inspiration, expiration, coughing and a Valsalva maneuver. A significant increase of portal venous pressure occurred during inspiration (+15%), coughing (+77%) and Valsalva maneuver (+157%). The value of portal venous‐esophageal luminal pressure gradient increased during inspiration (+38%), coughing (+90%) and Valsalva maneuver (+69%) while it decreased during expiration (–14%).