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Mucosal melanoma of the nasal cavity and paranasal sinuses
Author(s) -
Kingdom Todd T.,
Kaplan Michael J.
Publication year - 1995
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.2880170303
Subject(s) - medicine , paranasal sinuses , radiation therapy , surgery , nasal cavity , mucosal melanoma , melanoma , head and neck , cancer research
Background. Mucosal melanomas of the nasal cavity and paranasal sinuses are rare and do poorly. Methods. Seventeen patients treated from 1981 to 1993 at a single referral center were retrospectively reviewed. Results. Thirteen patients underwent surgical resection, with seven receiving postoperative radiotherapy. Eight had microscopically negative margins. The actuarial 2‐year and 5‐year survivals for this group of 13 were 67% (8 of 12) and 20% (2 of 10). The local recurrence rate was 85% (11 of 13) and distant metastases occurred in 31% (4 of 13) patients. In the absence of metastatic disease, resection of recurrent tumor correlated with disease‐free intervals ranging from 3 months to 40 months. Conclusions. Those who received postoperative radiotherapy appeared to have done better with increased disease‐free intervals and prolonged survival. Negative surgical margins were not predictive of a more favorable outcome. Surgical resection followed by postoperative radiotherapy is appropriate and resection of recurrent tumor should be considered. © 1995 Jons Wiley & Sons, Inc.