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Radiotherapy for basaloid squamous cell carcinoma of the head and neck
Author(s) -
Larner James M.,
Malcolm Ronald H.,
Mills Stacey E.,
Frierson Henry F.,
Banks Evelyn R.,
Levine Paul A.
Publication year - 1993
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.2880150314
Subject(s) - medicine , radiation therapy , head and neck , basal cell , head and neck cancer , head and neck squamous cell carcinoma , oncology , carcinoma , cancer , pathology , surgery
Basaloid squamous cell carcinoma (BSCC) of the head and neck is a recently described high‐grade variant of squamous cell carcinoma. It is a biologically virulent neoplasm with a propensity for nodal, as well as systemic, metastases. Because of the limited number of published reports, we reviewed data from patients of the University of Virginia Health Sciences Center and identified 16 cases of BSCC. The intent of this study was to determine the role of radiotherapy in the treatment of BSCC and better define the clinical features of this entity. Radiotherapy alone, or in combination with surgery, resulted in excellent local control rates. Distant metastases, chiefly pulmonary, occurred in more than half of the patients.