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Radiotherapy for adenoid cystic carcinoma of the palate
Author(s) -
Regine William F.,
Mendenhall William M.,
Parsons James T.,
Stringer Scott P.,
Cassisi Nicholas J.,
Million Rodney R.
Publication year - 1993
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.2880150312
Subject(s) - adenoid cystic carcinoma , radiation therapy , medicine , carcinoma , radiology
This is an analysis of 16 patients with adenoid cystic carcinoma of the palate who were treated with curative intent by radiotherapy alone (9) or surgery and radiotherapy (7). No patient received adjuvant chemotherapy. Follow‐up ranged from 3 years to 19 years with 69% of the patients having follow‐up of more than 5 years. Two patients in the radiotherapy alone group developed local recurrences, and both have had long‐term surgical salvage. No local failures were seen in the combined therapy group. Twelve patients (75%) are alive and disease‐free. Two patients died with distant disease, one within each treatment group. One patient in the combined therapy group is alive at 8 years with distant metastases, while one in the radiotherapy alone group died of intercurrent disease at 12 years. No significant complications were seen in either treatment group. The role of radiotherapy in the treatment of adenoid cystic carcinoma of the palate is reviewed.