Labeling index in squamous cell carcinoma of the larynx | Zendy

Balzi Manuela | Zendy; Ninu Benedetta M. | Zendy; Becciolini Aldo | Zendy; Scubla Elena | Zendy; Boanini Patrizia | Zendy; Gallina Ezio | Zendy; Gallo Oreste | Zendy; FiniStorchi Omero | Zendy; Bondi Roberto | Zendy

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Labeling index in squamous cell carcinoma of the larynx

Author(s) -

Balzi Manuela,

Ninu Benedetta M.,

Becciolini Aldo,

Scubla Elena,

Boanini Patrizia,

Gallina Ezio,

Gallo Oreste,

FiniStorchi Omero,

Bondi Roberto

Publication year - 1991

Publication title -

head and neck

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.012

H-Index - 127

eISSN - 1097-0347

pISSN - 1043-3074

DOI - 10.1002/hed.2880130413

Subject(s) - larynx , mitotic index , lymph , basal cell , pathology , stage (stratigraphy) , carcinoma , thymidine , cell , medicine , in vitro , biology , mitosis , anatomy , microbiology and biotechnology , biochemistry , paleontology

Two cell kinetic parameters, the 3 H‐thymidine labeling index (TLI) and the mitotic index (MI), were studied in vitro on fragments of squamous cell carcinoma tissue of the larynx. They were evaluated to identify those elements able to characterize the growth of these solid tumors. The values of these parameters were analyzed as a function of the clinical stage and the involvement of the regional lymph nodes. Results showed a statistically significant increase in the TLI from stage T1 to T3. No statistically significant differences in the TLI values were observed between the patients with positive and negative lymph nodes.

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