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Investigation of urinary transforming growth factor alpha levels as tumor markers in patients with advanced squamous cell carcinoma of the head and neck
Author(s) -
FazekasMay Mary,
Suen James Y.,
Yeh Yun Chi,
Yeh Hsing Wu,
Milligan Lynda Beth
Publication year - 1990
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.2880120507
Subject(s) - medicine , head and neck squamous cell carcinoma , urine , transforming growth factor , epidermoid carcinoma , basal cell , alpha (finance) , cancer , head and neck cancer , urinary system , carcinoma , oncology , pathology , surgery , construct validity , patient satisfaction
The objective of this study was to determine whether transforming growth factor alpha (TGF alpha) levels could be used as nonspecific tumor markers in patients with advanced squamous cell carcinoma (SCC) of the head and neck. Fourteen patients with epidermoid carcinoma of the head and neck were followed with serial urine TGF alpha levels, and the results were compared with the extent of cancer and the course of the disease. Based on the findings of this study further research is necessary before urine TGF levels can be recommended as a routine screening test for SCC of the head and neck.