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Transoral robotic surgery versus nonrobotic resection of oropharyngeal squamous cell carcinoma
Author(s) -
Chillakuru Yeshwant,
Benito Daniel A.,
Strum David,
Mehta Varun,
Saini Prashant,
Shim Timothy,
Darwish Christina,
Joshi Arjun S.,
Thakkar Punam,
Goodman Joseph F.
Publication year - 2021
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.26724
Subject(s) - transoral robotic surgery , medicine , neck dissection , oncology , retrospective cohort study , cohort , overall survival , basal cell , cancer , tongue , surgery , pathology
The aim of this study is to evaluate the impact of transoral robotic surgery (TORS) compared to nonrobotic surgery (NRS) on overall survival in oropharyngeal squamous cell carcinoma (OPSCC). We performed a retrospective study of patients with HPV+ and HPV− OPSCC undergoing TORS or NRS with neck dissection using the National Cancer Database from the years 2010–2016. Among patients with OPSCC in our cohort, 3167 (58.1%) patients underwent NRS and 2288 (41.9%) underwent TORS. TORS patients demonstrated better overall survival than NRS patients (HPV+ patients: aHR 0.74, p = 0.02; HPV− patients: aHR 0.58, p < 0.01). Subsite analysis showed TORS was correlated with improved survival in base of tongue (BoT) primaries for both HPV+ (aHR 0.46, p = 0.01) and HPV− (aHR 0.42, p = 0.01) OPSCC. Compared to NRS, TORS is associated with improved overall survival for HPV+ and HPV− OPSCC, as well as greater overall survival for BoT primaries.