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Salivary and lacrimal dysfunction after radioactive iodine for differentiated thyroid cancer: American Head and Neck Society Endocrine Surgery Section and Salivary Gland Section joint multidisciplinary clinical consensus statement of otolaryngology, ophthalmology, nuclear medicine and endocrinology
Author(s) -
Singer Michael C.,
Marchal Francis,
Angelos Peter,
Bernet Vic,
Boucai Laura,
Buchholzer Samanta,
Burkey Brian,
Eisele David,
Erkul Evren,
Faure Frederic,
Freitag Suzanne K.,
Gillespie Marion Boyd,
Harrell Richard Mack,
Hartl Dana,
Haymart Megan,
Leffert Jonathan,
Mandel Susan,
Miller Barbra S.,
Morris John,
Pearce Elizabeth N.,
Rahmati Rahmatullah,
Ryan William R.,
Schaitkin Barry,
Schlumberger Martin,
Stack Brendan C.,
Van Nostrand Doug,
Wong Ka Kit,
Randolph Gregory
Publication year - 2020
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.26417
Subject(s) - medicine , otorhinolaryngology , multidisciplinary approach , thyroid , head and neck cancer , complication , thyroid cancer , surgery , general surgery , intensive care medicine , radiation therapy , social science , sociology
Background Postoperative radioactive iodine (RAI) administration is widely utilized in patients with differentiated thyroid cancer. While beneficial in select patients, it is critical to recognize the potential negative sequelae of this treatment. The prevention, diagnosis, and management of the salivary and lacrimal complications of RAI exposure are addressed in this consensus statement. Methods A multidisciplinary panel of experts was convened under the auspices of the American Head and Neck Society Endocrine Surgery and Salivary Gland Sections. Following a comprehensive literature review to assess the current best evidence, this group developed six relevant consensus recommendations. Results Consensus recommendations on RAI were made in the areas of patient assessment, optimal utilization, complication prevention, and complication management. Conclusion Salivary and lacrimal complications secondary to RAI exposure are common and need to be weighed when considering its use. The recommendations included in this statement provide direction for approaches to minimize and manage these complications.

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