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Clinical utility of apparent diffusion coefficient and diffusion‐weighted magnetic resonance imaging for resectability assessment of head and neck tumors with skull base invasion
Author(s) -
Ogawa Takenori,
Kojima Ikuho,
Wakamori Shun,
Yoshida Takuya,
Murata Takaki,
Sakamoto Maya,
Ohkoshi Akira,
Nakanome Ayako,
Endo Hidenori,
Endo Toshiki,
Usubuchi Hajime,
Katori Yukio
Publication year - 2020
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.26336
Subject(s) - skull , magnetic resonance imaging , effective diffusion coefficient , medicine , pathological , head and neck , diffusion weighted magnetic resonance imaging , radiology , diffusion mri , head and neck cancer , nuclear medicine , pathology , anatomy , surgery , radiation therapy
Background The usefulness of apparent diffusion coefficient (ADC) and diffusion‐weighted magnetic resonance imaging (DWI) in the detection of malignant tumors has been reported. The purpose of this study is to clarify the role of ADC and DWI for diagnosis of skull base tumors. Methods A total of 27 patients with head and neck tumors with skull base invasions undergoing skull base surgery were enrolled in this study. Pathological findings of dural invasion and bone invasion were compared with the diagnostic imaging. Results Advanced magnetic resonance imaging techniques revealed that ADC values in regions of pathological bone and dural invasions were significantly lower than in regions of no invasion. The area under the curve of ADC in bone invasions and dural invasions were 0.957 and 0.894, respectively. Conclusions Our findings indicate that ADC and DWI are useful tools for the diagnosis of head and neck tumors with skull base invasion.