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Risk factors associated with the development of aspiration pneumonia in patients receiving radiotherapy for head and neck cancer: retrospective study
Author(s) -
Kawashita Yumiko,
Morimoto Shimpei,
Tashiro Kensuke,
Soutome Sakiko,
Yoshimatsu Masako,
Nakao Noriko,
Kurogi Tadafumi,
Saito Thoshiyuki,
Ukai Takashi,
Umeda Masahiro
Publication year - 2020
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.26314
Subject(s) - medicine , radiation therapy , aspiration pneumonia , head and neck cancer , pneumonia , mucositis , retrospective cohort study , incidence (geometry) , univariate analysis , surgery , risk factor , cancer , chemoradiotherapy , complication , multivariate analysis , physics , optics
Background Patients with head and neck cancer who are receiving radiotherapy can develop aspiration pneumonia. Determination of the incidence of aspiration pneumonia and the associated risk factors could facilitate the identification of high‐risk patients. Methods In this retrospective study, we determined the incidence of aspiration pneumonia in 357 patients receiving radiotherapy along with oral care for head and neck cancer. We also performed univariate and multivariable logistic regression analyses to investigate the risk factors for this complication. Results The incidence of aspiration pneumonia was 17.6%. Hypopharyngeal cancer, grade 3 oral mucositis, and nasogastric tube feeding were independent risk factors. Moreover, the development of aspiration pneumonia was one of the major effects on the discontinuation of radiotherapy. Conclusion Approximately, one‐sixth of the patients developed aspiration pneumonia despite appropriate oral care during radiotherapy for head and neck cancer. Aspiration pneumonia during radiotherapy could adversely affect head and neck cancer management.