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Respiratory and pulmonary complications in head and neck cancer patients: Evidence‐based review for the COVID‐19 era
Author(s) -
Silverman Dustin A.,
Lin Chen,
Tamaki Akina,
Puram Sidharth V.,
Carrau Ricardo L.,
Seim Nolan B.,
Eskander Antoine,
Rocco James W.,
Old Matthew O.,
Kang Stephen Y.
Publication year - 2020
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.26217
Subject(s) - medicine , intensive care medicine , adverse effect , lung cancer , respiratory system , disease , population , head and neck squamous cell carcinoma , head and neck cancer , cancer , environmental health
Abstract Background Pulmonary complications and infections frequently affect patients with head and neck squamous cell carcinoma (HNSCC). Common characteristics can predispose these patients to the development of severe respiratory illness, which may be particularly relevant during the 2019 coronavirus disease (COVID‐19) pandemic. Methods A scoping review was performed to assess the impact of pulmonary comorbidities and adverse respiratory outcomes in HNSCC patients. Results Advanced age, history of tobacco and alcohol abuse, and cardiopulmonary comorbidities are significant risk factors for the development of adverse respiratory outcomes. Treatment toxicities from radiation or chemoradiation therapy significantly increase these risks. Conclusion Respiratory complications are a frequent cause of morbidity and mortality among HNSCC patients, and the COVID‐19 pandemic may disproportionately affect this population. Interventions designed to decrease smoking and alcohol use, improve oral hygiene, and aggressively manage medical comorbidities are important to the long‐term management and health of these patients.