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Ceftriaxone‐induced radiation recall dermatitis
Author(s) -
Patel Nirav V.,
Samuels Michael,
Elsayyad Nagy
Publication year - 2020
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.26154
Subject(s) - medicine , ceftriaxone , dermatology , rash , antibiotics , radiation therapy , erythema , surgery , microbiology and biotechnology , biology
Background Radiation recall dermatitis (RRD) is an acute inflammatory skin reaction occurring in a skin area previously exposed to radiotherapy and triggered by subsequent intake of a drug, most commonly a chemotherapeutic agent. RRD secondary to antibiotics has also been reported but is a rare phenomenon overall and there are no reports of RRD in association with ceftriaxone exposure. Methods We report on a 59‐year‐old patient who had received radiotherapy to the neck bilaterally and who developed RRD 6 months later after a single dose of intramuscular ceftriaxone. Results The patient's rash resolved without further intervention over the ensuing 2 days following administration of a single dose of ceftriaxone. Conclusion This case illustrates that while RRD secondary to antibiotic exposure is rare, it is part of the differential diagnosis to be considered for acute dermatitis when there is a past history of radiotherapy to the same skin area.