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Outcomes after eye‐sparing surgery vs orbital exenteration in patients with lacrimal gland carcinoma
Author(s) -
Bonavolontà Paola,
Esmaeli Bita,
Donna Piero,
Tranfa Fausto,
Iuliano Adriana,
Abbate Vincenzo,
Fossataro Federica,
Attanasi Federica,
Bonavolontà Giulio
Publication year - 2020
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.26073
Subject(s) - medicine , lacrimal gland , surgery , carcinoma , distant metastasis , eye disease , metastasis , cancer , pathology
Abstract Background This study examined whether eye‐sparing surgery is associated with better or worse outcomes than exenteration for the treatment of lacrimal gland carcinomas. Methods Forty‐six patients treated for lacrimal gland carcinoma were retrospectively reviewed and compared. A statistical analysis was performed using Kaplan‐Meier plots. Results The overall survival rates for eye‐sparing surgery were 52% and 37% at 5 and 10 years, and those for exenteration were 37% and 25% at 5 and 10 years, respectively ( P = .73). The proportion of patients with local regional control at both 5 and 10 years after eye‐sparing surgery was 0.75, and that for exenteration was 0.47 ( P = .30). For eye‐sparing surgery, the proportions of distant metastasis‐free survival at 5 and 10 years were 0.51 and 0.39 for eye‐sparing surgery and 0.29 and 0.14 for exenteration ( P = .50). Conclusion Because the outcomes were not significantly different, the authors suggest that eye‐sparing surgery can be proposed as a reasonable approach for lacrimal gland carcinomas in appropriately selected patients.