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Recurrence factors in pediatric ameloblastoma: Clinical features and a new classification system
Author(s) -
Yang Rong,
Tang Yu,
Zhang Xu,
Liu Zheqi,
Gokavarapu Sandhya,
Lin Chengzhong,
Ren Zhenhu,
Zhou Yongmei,
Cao Wei,
Ji Tong
Publication year - 2019
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.25867
Subject(s) - ameloblastoma , medicine , youden's j statistic , soft tissue , receiver operating characteristic , retrospective cohort study , root resorption , resorption , dentistry , radiology , surgery , pathology , maxilla
Background Ameloblastomas of jaw in the pediatric population are a rare clinical entity and have not been well addressed in the literatures. The present retrospective study analyzed the risk factors associated with recurrence of pediatric ameloblastomas. Methods Cases of primary pediatric ameloblastomas seen in a tertiary hospital between 2005 and 2015 were analyzed to identify the clinical factors associated with recurrence. Results There were a total of 104 cases of primary pediatric ameloblastomas. The overall mean maximum tumor diameter was 4.11 ± 1.339 cm. The receiver operating characteristic curve and the Youden Index showed an optimal cutoff point of 4.95 cm to accurately predict recurrence. Bone cortex/soft tissue invasion were associated with tumor recurrence ( P < .001). Conclusions The maximum tumor diameter, root resorption, and bone cortex/soft tissue invasion were risk factors for recurrence of pediatric ameloblastomas. The new classification system may serve as a predictor of recurrence in pediatric ameloblastomas.