Premium
Postoperative radiation performed at the same surgical facility associated with improved overall survival in oral cavity squamous cell carcinoma
Author(s) -
Amini Arya,
Stokes William A.,
Jones Bernard L.,
Sampath Sagus,
Kang Robert S.,
Ger Thomas J.,
Maghami Ellie G.,
Massarelli Erminia,
Bradley Cathy J.,
Karam Sana D.
Publication year - 2019
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.25697
Subject(s) - medicine , port (circuit theory) , head and neck cancer , overall survival , hazard ratio , surgery , basal cell , propensity score matching , multivariate analysis , cancer , radiation therapy , confidence interval , electrical engineering , engineering
Background The purpose of this analysis is to evaluate whether postoperative radiotherapy (PORT) at the same facility as surgery portends to better survival outcomes compared to PORT given at a different facility. Methods Patients underwent upfront surgery at the National Cancer Database reporting facility followed by PORT. PORT was coded as performed at either the same facility or at a different facility as surgery. Results A total of 10 832 patients were selected. Five‐year overall survival (OS) was higher in patients undergoing PORT at the same facility: 52.5% vs 48.4% ( P < 0.001). PORT performed at the same facility was associated with improved OS under multivariate (HR, 0.92; P = 0.01) and propensity score matched (hazard ratio, 0.90; P = 0.004) analyses. Conclusions OS was better among patients with head and neck cancer who received PORT at the same facility as surgery.