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Effect of radiotherapy on the chemical composition of root dentin
Author(s) -
Campi Lívia Bueno,
Lopes Fabiane Carneiro,
Soares Luís Eduardo Silva,
Queiroz Alexandra Mussolino,
Oliveira Harley Francisco,
Saquy Paulo César,
SousaNeto Manoel Damião
Publication year - 2019
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.25493
Subject(s) - dentin , amide , chemistry , nuclear chemistry , carbonate , raman spectroscopy , phosphate , demineralization , irradiation , dentistry , cementum , chemical composition , enamel paint , organic chemistry , medicine , physics , nuclear physics , optics
Abstract Background The radiotherapy can directly affect the bond strength of the adhesive materials, interfering in the prognosis of restorative treatments, which may be caused by chemical changes in dentin structure. Methods Twenty inferior homologues premolars were distributed in 2 groups (in vitro study) ( n = 10): nonirradiated and irradiated. The specimens were submitted to the analysis of phosphate (ν 1 PO 4 3− ;ν 2 PO 4 3− ;ν 4 PO 4 3− ), carbonate (ν 3 CO 3 2− ), amide I, CH 2 , amide III, and amide I/III ratio by confocal Raman spectroscopy. Data were submitted to statistical analysis (T test, P < .05). Results In intracanal dentin, the irradiated group had lower ν 4 PO 4 3− values (1.23 ± 0.06) compared to nonirradiated group (1.40 ± 0.18) ( P < .05), with no difference for ν 1 PO 4 3− and ν 2 PO 4 3 peaks ( P > .05). The irradiated (1.56 ± 0.06) had lower carbonate, amide III (1.05 ± 0.19), and amide I/III ratio values (0.19 ± 0.06) compared to nonirradiated group (1.42 ± 0.10, 1.28 ± 0.24, and 0.31 ± 0.10, respectively) ( P < .05). For medium dentin irradiated group (1.30 ± 0.12) had lower phosphate values compared to nonirradiated group (1.48 ± 0.22) ( P < .05). In cementum, there was no statistical difference between the groups. Conclusion The radiotherapy was able to cause changes in ν 4 PO 4 3− , carbonate, and amide III peaks of root dentin.