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18 F‐FDG PET/MRI vs MRI in patients with recurrent adenoid cystic carcinoma
Author(s) -
Kirchner Julian,
Schaarschmidt Benedikt M.,
Sauerwein Wolfgang,
Deuschl Cornelius,
ArweilerHarbeck Diana,
Holtmann Laura,
Stebner Vanessa,
Umutlu Lale,
Antoch Gerald,
Ruhlmann Verena
Publication year - 2019
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.25485
Subject(s) - adenoid cystic carcinoma , medicine , nuclear medicine , radiology , carcinoma , pathology
Objectives To evaluate and compare the diagnostic potential of 18 F‐fluorodeoxyglucose positron emission tomography/magnetic resonance imaging ( 18 FDG‐PET/MRI) and MRI for recurrence diagnostics after primary therapy in patients with adenoid cystic carcinoma (ACC). Methods A total of 32 dedicated head and neck 18 F‐FDG PET/MRI datasets were included in this analysis. MRI and 18 F‐FDG PET/MRI datasets were analyzed in separate sessions by two readers for tumor recurrence or metastases. Results Lesion‐based sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy were 96%, 84%, 90%, 93%, and 91% for 18 F‐FDG PET/MRI and 77%, 94%, 95%, 73%, and 84% for MRI, resulting in a significantly higher diagnostic accuracy of 18 F‐FDG PET/MRI compared to MRI ( P < .005). Conclusion 18 F‐FDG PET/MRI is superior to MRI in detecting local recurrence and metastases in patients with ACC of the head and neck. Especially concerning its negative predictive value, 18 F‐FDG PET/MRI outperforms MRI.