18 F‐FDG PET/MRI vs MRI in patients with recurrent adenoid cystic carcinoma | Zendy

Kirchner Julian | Zendy; Schaarschmidt Benedikt M. | Zendy; Sauerwein Wolfgang | Zendy; Deuschl Cornelius | Zendy; ArweilerHarbeck Diana | Zendy; Holtmann Laura | Zendy; Stebner Vanessa | Zendy; Umutlu Lale | Zendy; Antoch Gerald | Zendy; Ruhlmann Verena | Zendy

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18 F‐FDG PET/MRI vs MRI in patients with recurrent adenoid cystic carcinoma

Author(s) -

Kirchner Julian,

Schaarschmidt Benedikt M.,

Sauerwein Wolfgang,

Deuschl Cornelius,

ArweilerHarbeck Diana,

Holtmann Laura,

Stebner Vanessa,

Umutlu Lale,

Antoch Gerald,

Ruhlmann Verena

Publication year - 2019

Publication title -

head and neck

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.012

H-Index - 127

eISSN - 1097-0347

pISSN - 1043-3074

DOI - 10.1002/hed.25485

Subject(s) - adenoid cystic carcinoma , medicine , nuclear medicine , radiology , carcinoma , pathology

Objectives To evaluate and compare the diagnostic potential of 18 F‐fluorodeoxyglucose positron emission tomography/magnetic resonance imaging ( 18 FDG‐PET/MRI) and MRI for recurrence diagnostics after primary therapy in patients with adenoid cystic carcinoma (ACC). Methods A total of 32 dedicated head and neck 18 F‐FDG PET/MRI datasets were included in this analysis. MRI and 18 F‐FDG PET/MRI datasets were analyzed in separate sessions by two readers for tumor recurrence or metastases. Results Lesion‐based sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy were 96%, 84%, 90%, 93%, and 91% for 18 F‐FDG PET/MRI and 77%, 94%, 95%, 73%, and 84% for MRI, resulting in a significantly higher diagnostic accuracy of 18 F‐FDG PET/MRI compared to MRI ( P < .005). Conclusion 18 F‐FDG PET/MRI is superior to MRI in detecting local recurrence and metastases in patients with ACC of the head and neck. Especially concerning its negative predictive value, 18 F‐FDG PET/MRI outperforms MRI.

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