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Compartmental surgery for oral tongue and floor of the mouth cancer: Oncologic outcomes
Author(s) -
Piazza Cesare,
Grammatica Alberto,
Montalto Nausica,
Paderno Alberto,
Del Bon Francesca,
Nicolai Piero
Publication year - 2019
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.25480
Subject(s) - medicine , neurovascular bundle , tongue , floor of mouth , basal cell , cancer , overall survival , surgery , retrospective cohort study , tongue neoplasm , observational study , oncology , pathology
Background Oral tongue/floor of mouth squamous cell carcinoma (OTFMSCC) with a depth of invasion (DOI) > 10 mm involves extrinsic muscles and lingual neurovascular/lymphatic bundles. “Compartmental” hemiglossopelvectomy (CHGP) was developed to improve loco‐regional control by “en bloc” removal of tumor and its pathways of spread. Methods We conducted a retrospective observational study on 45 CHGPs performed at a single institution for OTFMSCC with a DOI > 10 mm at CT/MR. Group A ( n = 35) included naïve patients, and group B ( n = 10) recurrent cancers. We evaluated 2‐year overall survival (OS), disease‐free survival (DFS), local control (LC), and loco‐regional control (LRC). Results Two‐year OS, DFS, LC, and LRC were 80%, 91%, 100%, and 94% for group A, and 27%, 26%, 67%, and 36% for group B, respectively. Salvage surgery and positive margins were significantly associated with worse prognosis. Conclusion CHGP is a reliable oncologic approach in primary surgery for advanced OTFMSCC. In recurrent cancers, survival remains poor.