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Diffusion weighted imaging of esthesioneuroblastoma: Differentiation from other sinonasal masses
Author(s) -
Miracle Aaron C.,
ElSayed Ivan H.,
Glastonbury Christine M.
Publication year - 2019
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.25365
Subject(s) - esthesioneuroblastoma , medicine , effective diffusion coefficient , diffusion mri , nuclear medicine , radiology , magnetic resonance imaging , pathology , radiation therapy
Background Differentiating esthesioneuroblastoma (ENB) from other sinonasal tumors is difficult by MRI. We tested whether diffusion weighted imaging (DWI) could distinguish ENB from other sinonasal tumors. Methods Hundred forty‐six patients underwent sinonasal MRI, 75 with technically successful DWI. Pathology: 18 ENB (24%), 34 (45%) other malignant tumors, and 23 (31%) benign lesions. Apparent diffusion coefficients (ADCs) were calculated. Results Average ADC and normalized ADC of ENB (1.22 × 10 −3 ± 0.28 mm 2 /s and 1.55 ± 0.36, respectively) were higher than other malignancies (0.98 × 10 −3 ± 0.18 mm 2 /s and 1.31 ± 0.29, P = .002 and P = .034) and lower than benign disease (1.92 × 10 −3 ± 0.33 mm 2 /s and 2.44 ± 0.50, P < .0001). ADC differentiated ENB from benign disease with 91% sensitivity and 83% specificity. An ADC cutoff of 1.1 × 10 −3 mm 2 /s differentiated other malignancies from ENB with 72% sensitivity and 85% specificity. Conclusions DWI is useful in distinguishing ENB from other sinonasal disease.