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AHNS Series: Do you know your guidelines? Principles of treatment for locally advanced or unresectable head and neck squamous cell carcinoma
Author(s) -
Fulcher Cory D.,
Haigentz Missak,
Ow Thomas J.
Publication year - 2018
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.25025
Subject(s) - medicine , head and neck cancer , larynx , limiting , head and neck , basal cell , radiation therapy , cancer , oncology , head and neck squamous cell carcinoma , human papillomavirus , chemotherapy , general surgery , surgery , mechanical engineering , engineering
This article is a continuation of the “Do You Know Your Guidelines” series, initiated by the Education committee of the American Head and Neck Society. Treatment guidelines for advanced head and neck squamous cell carcinoma are reviewed here, including the critical roles of radiotherapy, chemotherapy, and the recent application of immunotherapy agents. We will be limiting this discussion to include cancers of the oral cavity, oropharynx, hypopharynx, and larynx. It should be noted that much of the article pertains to human papillomavirus (HPV)‐negative oropharyngeal cancer where applicable, as HPV‐positive oropharyngeal squamous cell carcinoma carries a different natural history, different prognosis, and now different staging criteria. Additionally, the article will not include information on nasopharyngeal or sinus cancers, as these latter topics are covered in separate “Do you know your guidelines?” installments and these diagnoses carry somewhat different approaches to diagnosis and management that diverge from the focus of this article.