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Life quality improvement in hoarse patients with early glottic cancer after transoral laser microsurgery
Author(s) -
Hsin LiJen,
Lin WanNi,
Fang TuanJen,
Lee LiAng,
Kang ChungJan,
Huang BingShan,
Lin ChienYu,
Fan KangHsing,
Tsang NganMing,
Hsu ChengLung,
Chang Joseph TungChieh,
Liao ChunTa,
Yen TzuChen,
Chang KaiPing,
Chuang HsiuFeng,
Li HsuehYu
Publication year - 2017
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.24873
Subject(s) - medicine , transoral laser microsurgery , quality of life (healthcare) , prospective cohort study , microsurgery , cohort , larynx , cancer , audiology , cohort study , surgery , laryngeal neoplasm , nursing
Background The purpose of this study was to evaluate the recovery kinetics of voice and quality of life (QOL) over time in patients with early glottic cancer who underwent transoral laser microsurgery (TLM). Methods A prospective cohort study was conducted in which acoustic and aerodynamic voice assessments and QOL analyses were done using health‐related questionnaires (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire‐Core 30‐questions [EORTC‐QLQ‐C30] and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire‐Head and Neck 35‐questions [EORTC‐QLQ‐H&N35]) were administered at designated times. Results Most voice laboratory parameters worsened during the first month, then recovered to baseline after 6 months. The QLQ‐H&N35 speech subscale was significantly improved. Among the voice laboratory parameters, pretreatment harmonics‐to‐noise ratio was an independent predictor ( P = .041) for improvement on the speech subscale at the endpoint. Conclusion Despite an initial deterioration of voice and QOL in the first month, patients who underwent TLM recovered to a plateau since the sixth month and then to better than preoperative status afterward. A greater improvement in QOL was seen in patients with poorer baseline voice quality.